LICHENOID DYSPLASIA PDF

Corresponding author. Received Nov 28; Accepted Dec Abstract Lichenoid changes in the oral mucosa can be encountered in a wide range of lesions with varied etiologies including immune-mediated disorders, reactions to systemic medications and to dental materials. Dysplasia of the oral cavity can exhibit a lichenoid histology, which may mask the potentially cancerous component.

Author:Faezil Faegrel
Country:Guyana
Language:English (Spanish)
Genre:History
Published (Last):20 February 2017
Pages:492
PDF File Size:20.47 Mb
ePub File Size:17.51 Mb
ISBN:676-2-88631-911-9
Downloads:1060
Price:Free* [*Free Regsitration Required]
Uploader:Tegar



Corresponding author. Received Nov 28; Accepted Dec Abstract Lichenoid changes in the oral mucosa can be encountered in a wide range of lesions with varied etiologies including immune-mediated disorders, reactions to systemic medications and to dental materials. Dysplasia of the oral cavity can exhibit a lichenoid histology, which may mask the potentially cancerous component.

Another unusual clinical disease, proliferative verrucous leukoplakia, can often mimic oral lichen planus clinically requiring careful correlation of the clinical and pathologic features.

Keywords: Lichen planus, Lichenoid reactions, Oral dysplasia, Proliferative verrucous leukoplakia Introduction An immune mediated disease of unknown etiology oral lichen planus OLP is a chronic inflammatory disease of variable severity that can wax and wane over a long period of time. A number of clinical as well as microscopic mimics of OLP exist making diagnosis challenging at times.

Oral lichenoid lesions from systemic drug exposure or local allergic contact hypersensitivity are well documented [ 1 ]. Other immune-mediated diseases including mucous membrane pemphigoid, graft versus host disease, and lupus erythematosus can share common clinical and histological features with OLP [ 2 ].

Oral lichenoid lesions requires that both the clinician and pathologist have broad experience of the varied clinical presentations to develop an accurate differential diagnoses. The exact incidence of malignant transformation of OLP is unknown although there have been a few well-documented cases [ 3 ].

Similar to lichen planus, lichenoid dysplasias exhibit a prominent band-like, chronic inflammatory cell infiltrate subjacent to the basal cells. Proliferative verrucous leukoplakia, both a clinical and microscopic mimic of OLP needs to be considered when a patient with multiple oral lichenoid lesions shows histologically varying degrees of dysplasia, verrucous carcinoma, or conventional squamous cell carcinoma [ 5 ]. Discussion Oral Lichen Planus Lichen planus is a relatively common immune-mediated disease and next to cutaneous lichen planus, the oral lesions are the most common presentation.

In the oral cavity there are three major clinical presentations: reticular, erythematous, and erosive Fig.

DULUTH GORE VIDAL PDF

Lichenoid dysplasia: a distinct histopathologic entity.

Oral mucosal lesions associated with dysplasia Leukoplakia Oral leukoplakia according to the World Health Organisation definition is a white patch or plaque that cannot be characterised, clinically or histopathologically , as any other disease. There are a number of possible causes for white patch oral mucosal lesions and similar looking such lesions are quite common. Leukoplakic patches can appear in all areas of the mouth but the side of the tongue and the floor of the mouth see Figure 1 are common locations. Leukoplakic patches come in a range of appearances and may be completely asymptomatic or cause symptoms. Figure 1: Leukoplakia of the floor of the mouth. Erythroplakia Erythroplakia is defined as a red patch see Figure 2 that cannot be diagnosed as any other lesion.

CIENCIA E ENGENHARIA DOS MATERIAIS CALLISTER PDF

Oral Manifestations of Dermatologic Disease: A Focus on Lichenoid Lesions

.

BHAGTAN DI BANI PDF

Lichenoid Keratosis

.

KITAB AZKAR PDF

.

Related Articles