Summary of Cissus quadrangularis Primary information, health benefits, side effects, usage, and other important details Cissus quadrangularis is a traditional medicine usually said to come from Ayurveda but appears to have a wide range of locations which have used it medicinally due to it growing in numerous locations. It is most frequently used by athletes, and the anecdotes of cissus seem to precede much of the science on the topic. It appears to be a very effective pain killer in rodent studies, but at this moment in time only one preliminary study has been conducted in humans; while it showed promise in athletes who experienced joint pain due to exercise by reducing overall joint symptoms by about a third it was still a lone study. More research is needed, but it seems promising as an alterative for joint pain in athletes since most joint health supplements do not have evidence in athletes rather, most research is in osteoarthritis persons. Although a potential complication in athletes is that preliminary rodent evidence suggests that cissus has sedative and muscle relaxing properties at high doses active within 30 minutes of ingestion , suggesting that it might not make the best pre-workout supplement.

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The preliminary phytochemical screening of the stem and leaf shows they do not contain alkaloids. The plant contains calcium oxalate5 and the root contains the anthocyanins flavonoids : cyanidin and delphinin6.

The resulting oil extract caused a significant inhibition 32 mm halo in the culture of Staphylococcus aureus ATCC on agar plate. However, the oil extract prepared by adding fresh crushed leaf 6 g to 1 mL of oil that had been previously heated did not induce inhibition of bacterial growth. It did not report antimicrobial activity in vitro against Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa orAspergillus niger.

It did not modify blood pressure or heart rate. The aqueous extract from the leaf was stimulant towards isolated uterus of rat 0. Laboratorio enda-caribe, Santo Domingo, Rep. J Food Sci 48 4 Salvador Allende", La Habana, Cuba. J Pharm Pharmacol Lloydia Anti-inflammatory activity of Agave intermixta Trel. J Ethnopharmacol 71 3 : It is not intended to take the place of either the written law or regulations. Since some parts of plants could be toxic, might induce side effects, or might have interactions with certain drugs, anyone intending to use them or their products must first consult with a physician or another qualified health care professional.

TRAMIL has no responsibility whatsoever towards the user for any decision, action or omission made in relation to the information contained in this Pharmacopoeia.


Cissus quadrangularis



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